1. **Explain the Indian Removal Act of 1830 and President Andrew Jackson's role.**
The Indian Removal Act was signed into law by President Andrew Jackson on May 28, 1830, which authorized the president to grant lands west of the Mississippi in exchange for Indian lands within existing state borders [S3], [S4]. President Andrew Jackson informed Congress on the progress of the removal of Indian tribes living east of the Mississippi River to land in the west in his annual message to Congress on December 6, 1830, and signed the Indian Removal Act of May 28, 1830, which was the first major step to relocate American Indians [S4].

2. **Explain Worcester v. Georgia, the Treaty of New Echota, Cherokee opposition to the treaty, and the eventual forced removal.**
The Cherokee Nation attempted to protect their lands by assimilating into European-American culture as much as possible since the early 1800s [S2]. Gold was found in the Cherokee Nation, which prompted people to want that land [S2]. The Treaty of New Echota was a document that the Cherokee Nation opposed [S2]. Chief John Ross protested the Treaty of New Echota [S2].

3. **Give historically supported estimates for the number of Cherokee removed and deaths associated with removal.**
The supplied evidence does not establish historically supported estimates for the number of Cherokee removed and deaths associated with removal.

4. **Describe conditions during detention and removal.**
The supplied evidence